Brain Inflammation and Alzheimer's-Like Pathology in Individuals Exposed to Severe Air Pollution

@article{CaldernGarcidueas2004BrainIA,
  title={Brain Inflammation and Alzheimer's-Like Pathology in Individuals Exposed to Severe Air Pollution},
  author={Lilian Calder{\'o}n-Garcidue{\~n}as and William Reed and Robert R. Maronpot and Carlos F. Henr{\'i}quez-Rold{\'a}n and Ricardo Delgado-Ch{\'a}vez and Ana Laura Calder{\'o}n-Garcidue{\~n}as and Irma Dragustinovis and Maricela Franco-Lira and Mariana Arag{\'o}n-Flores and Anna C Solt and Michael K. Altenburg and Ricardo Torres‐Jard{\'o}n and James A. Swenberg},
  journal={Toxicologic Pathology},
  year={2004},
  volume={32},
  pages={650 - 658}
}
Air pollution is a complex mixture of gases (e.g., ozone), particulate matter, and organic compounds present in outdoor and indoor air. Dogs exposed to severe air pollution exhibit chronic inflammation and acceleration of Alzheimer's-like pathology, suggesting that the brain is adversely affected by pollutants. We investigated whether residency in cities with high levels of air pollution is associated with human brain inflammation. Expression of cyclooxygenase-2 (COX2), an inflammatory mediator… 

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