Brain Correlates of Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI)

@inproceedings{James2016BrainCO,
  title={Brain Correlates of Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI)},
  author={Lisa M James and Brian E. Engdahl and Arthur C. Leuthold and Apostolos P. Georgopoulos},
  booktitle={EBioMedicine},
  year={2016}
}
BACKGROUND We recently reported that six alleles from class II genes of the Human Leukocyte Antigen (HLA) confer protection from Gulf War Illness (GWI) (Georgopoulos et al., 2015). The most significant effect is exerted on Neurological-Cognitive-Mood (NCM), Pain, and Fatigue symptoms, such that higher number of copies of the protective alleles are associated with lower symptom severity. Here we tested the hypothesis that this effect is exerted by modulating the strength of neural synchronicity… CONTINUE READING
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