Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications

@article{AbouAntoun2017BrainCS,
  title={Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications},
  author={Tamara J Abou-Antoun and James Scott Hale and Justin D Lathia and Stephen M. Dombrowski},
  journal={Neurotherapeutics},
  year={2017},
  volume={14},
  pages={372-384}
}
Brain tumors represent some of the most malignant cancers in both children and adults. Current treatment options target the majority of tumor cells but do not adequately target self-renewing cancer stem cells (CSCs). CSCs have been reported to resist the most aggressive radiation and chemotherapies, and give rise to recurrent, treatment-resistant secondary… CONTINUE READING