Brain, aging and neurodegeneration: Role of zinc ion availability

  title={Brain, aging and neurodegeneration: Role of zinc ion availability},
  author={Eugenio Mocchegiani and Carlo Bertoni-Freddari and F. Marcellini and Marco Malavolta},
  journal={Progress in Neurobiology},
Actual fields of research in neurobiology are not only aimed at understanding the different aspects of brain aging but also at developing strategies useful to preserve brain compensatory capacity and to prevent the onset of neurodegenerative diseases. Consistent with this trend much attention has been addressed to zinc metabolism. In fact, zinc acts as a neuromodulator at excitatory synapses and has a considerable role in the stress response and in the functionality of zinc-dependent enzymes… CONTINUE READING


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