Bradykinin in blood and cerebrospinal fluid after acute cerebral lesions: correlations with cerebral edema and intracranial pressure.

@article{Kunz2013BradykininIB,
  title={Bradykinin in blood and cerebrospinal fluid after acute cerebral lesions: correlations with cerebral edema and intracranial pressure.},
  author={Mathias Kunz and Juerg Nussberger and M Holtmannsp{\"o}tter and H. Bitterling and Nikolaus Plesnila and Stefan Zausinger},
  journal={Journal of neurotrauma},
  year={2013},
  volume={30 19},
  pages={1638-44}
}
Bradykinin (BK) was shown to stimulate the production of physiologically active metabolites, blood-brain barrier disruption, and brain edema. The aim of this prospective study was to measure BK concentrations in blood and cerebrospinal fluid (CSF) of patients with traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), and ischemic stroke and to correlate BK levels with the extent of cerebral edema and intracranial pressure (ICP). Blood and CSF samples of 29… CONTINUE READING