Bradykinin antagonists: development and applications.

@article{Stewart1995BradykininAD,
  title={Bradykinin antagonists: development and applications.},
  author={John M Stewart},
  journal={Biopolymers},
  year={1995},
  volume={37 2},
  pages={143-55}
}
Bradykinin (BK) is involved in regulation of every major physiological system and is an initiator or mediator of many pathophysiological conditions. Rapid progress in understanding these aspects of BK biology has come since the discovery of BK antagonists. This article reviews principal points in the history of the kallikrein-kinin field and of kinin biology. The chemistry and development of antagonists for B1 and B2 kinin receptors is discussed. Uses of the antagonists in biomedical research… CONTINUE READING

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