Brachytherapy-mediated bone damage in a rat model investigating maxillary osteoradionecrosis.

Abstract

OBJECTIVES To assess clinical and radiologic findings from targeted radiotherapy to the rat maxilla and to compare findings with a recently developed rat model of mandibular osteoradionecrosis (ORN). DESIGN A prospective, controlled animal study. SUBJECTS Ten male Sprague-Dawley rats were divided into an experimental group receiving catheter-assisted… (More)
DOI: 10.1001/archoto.2011.1176

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