Brønsted acid activation of alpha-diazo imide: a syn-selective glycolate Mannich reaction.
Timothy L Troyer
Jeffrey N Johnston
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Abstract & Figures
A novel alpha-diazo imide reagent and its activation by strong Brønsted acid is shown to produce the product of a syn-glycolate Mannich transform with high diastereoselection.
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a-oxy ketone nucleophiles
Adv. Synth. Catal.,
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