BpeAB-OprB, a multidrug efflux pump in Burkholderia pseudomallei.

  title={BpeAB-OprB, a multidrug efflux pump in Burkholderia pseudomallei.},
  author={Ying Ying Chan and Theresa May Chin Tan and Yong Mei Ong and Kim Lee Chua},
  journal={Antimicrobial agents and chemotherapy},
  volume={48 4},
Burkholderia pseudomallei, the causative agent of melioidosis, is intrinsically resistant to a wide range of antimicrobial agents, including beta-lactams, aminoglycosides, macrolides, and polymyxins. An operon, bpeR-bpeA-bpeB-oprB, which encodes a putative repressor, a membrane fusion protein, an inner membrane protein, and an outer membrane protein, respectively, of a multidrug efflux pump of the resistance-nodulation-division family was identified in B. pseudomallei. The divergently… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 43 extracted citations

A census of RND superfamily proteins in the Burkholderia genus.

Future microbiology • 2013
View 3 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 34 references

Evaluation of methods for the prediction of membrane spanning regions

R. A. Moore, D. DeShazer, S. Reckseidler, A. Weissman, D. E. Woods
Bioinformatics • 2001

Molecular cloning: a laboratory manual, 3rd ed

J. Sambrook, D. W. Russell
View 1 Excerpt

Similar Papers

Loading similar papers…