Bowen's disease showing spontaneous complete regression associated with apoptosis.

Abstract

Spontaneous regression is sometimes seen in malignant skin tumours. We report a 68-year-old woman whose Bowen's disease showed spontaneous complete regression. Prominent infiltration of T cells and increased vascularity were found in the upper dermis of the regressed lesion. Strong expression of Fas (APO-1/CD95) antigen, an apoptosis-related tumour necrosis factor receptor family protein, in the primary lesion and faint expression following regression suggest the involvement of Fas-mediated apoptosis in the spontaneous complete regression of our patient's Bowen's disease.

Cite this paper

@article{Chisiki1999BowensDS, title={Bowen's disease showing spontaneous complete regression associated with apoptosis.}, author={M Chisiki and Akira Kawada and Masashi Akiyama and Yoshito Itoh and Shingo Tajima and Akira Ishibashi and F Yudate}, journal={The British journal of dermatology}, year={1999}, volume={140 5}, pages={939-44} }