Bovine viral diarrhoea virus genotype 1 can be separated into at least eleven genetic groups

  title={Bovine viral diarrhoea virus genotype 1 can be separated into at least eleven genetic groups},
  author={Stefan Vilcek and David J. Paton and Branislav Durkovic and Ladislav Strojn{\'y} and Georgina Ibata and Amal Moussa and Angelika Loitsch and W Rossmanith and Santiago Vega and Maria Teresa Scicluna and Vilmos P{\'a}lfi},
  journal={Archives of Virology},
Summary. Seventy-eight bovine viral diarrhoea viruses (BVDV) recently collected in Austria, France, Hungary, Italy, Slovakia, Spain and UK were genetically typed in the 5′-untranslated (5′UTR) and autoprotease (Npro) regions of the pestivirus genome. Seventy-six of the isolates were BVDV-1 and two French isolates were of the BVDV-2 genotype. Phylogenetic analysis of the 5′UTR (245 nt), including additional BVDV-1 sequences from USA, Canada, Germany, New Zealand, Mozambique and Sweden, taken… 

Genetic Heterogeneity of Bovine Viral Diarrhoea Virus In Italy

The genetic characteristics, of 38 field isolates of bovine viral diarrhoea virus (BVDV) collected in 1999 from sick or healthy and persistently infected cattle of dairy farms situated in northern Italy, provided evidence for genetic heterogeneity of BVDV in Italy.

Genetic diversity of international bovine viral diarrhoea virus (BVDV) isolates: identification of a new BVDV-1 genetic group.

To find out whether genetic grouping of isolates from different countries could be harmonised, 22 new isolate from five countries were analysed in combination with published sequences and it was found that these isolates fall into the same group as a deer strain, and are statistically significant.

Genetic diversity of bovine viral diarrhoea virus (BVDV) from Peru and Chile

Twenty-five BVDV strains, detected in serum from persistently infected cattle from Peru and Chile were genetically characterized, and phylogenetic analysis based on the 5' UTR showed that all 25 strains belonged to genotype 1, which is the predominant BVDVs subtype in many countries all over the world, including USA.

Genetic Diversity of Bovine Viral Diarrhea Virus 1: Italian Isolates Clustered in at Least Seven Subgenotypes

Type 88 BVD viruses found throughout Italy were found to belong to 7 distinct subgenotypes, and the occurrence of BVDV-2 was also reconfirmed.

Genetic heterogeneity of bovine viral diarrhoea viruses from Spain.




Genetic heterogeneity of bovine viral diarrhoea viruses isolated in Southern Africa.

Genetic typing of bovine pestiviruses from England and Wales.

Molecular characterization of ovine pestiviruses.

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Segregation of bovine viral diarrhea virus into genotypes.

Isolates of bovine viral diarrhea virus (BVDV) were segregated into two groups based on comparison of sequences from the 5' untranslated region (UTR) of the viral genome, suggesting that these groups are as different from each other as reference BVDV are from hog cholera virus.

Genomic (5′UTR) and serological differences among German BVDV field isolates

SummaryIsolates of bovine viral diarrhoea virus (BVDV) collected in Germany were examined for their genomic heterogeneity in sequences from the 5′untranslated region (UTR) of the viral genome.

Genetic diversity of pestiviruses: identification of novel groups and implications for classification.

The complete Npro coding sequences were determined for 16 pestiviruses isolated from cattle, pig, and several wild ruminant species including reindeer, bison, deer, and bongo, and Interestingly, the isolates from reindeers and bison are distinct from the established pestivirus species.

A proposed division of the pestivirus genus using monoclonal antibodies, supported by cross-neutralisation assays and genetic sequencing.

Four principal virus subgroups were demonstrated and genetic comparisons between representative viruses from the 4 subgroups and by virus neutralisation with polyclonal sera supported the subgrouping scheme.

Genetic typing of pestiviruses from New Zealand.

The findings show that the evolution of pestiviruses in New Zealand has been similar to Europe and North America, indicating the occurrence of a conservative phylogenetic branch of BVDV type I in cattle and the presence of BDV in the sheep population.

Genotypic Analysis of the 5′‐Untranslated Region of a Pestivirus Strain Isolated from Human Leucocytes

The 5′‐untranslated genomic region of the pestivirus strain Europa, originated in human leucocytes and previously identified as bovine diarrhea virus, was amplified by reverse transcription‐PCR and sequenced and revealed that this human isolate should be assigned to a novel genotype of pestiv virus, type Ic.