Bovine respiratory syncytial virus ISCOMs-Immunity, protection and safety in young conventional calves.

@article{Hgglund2011BovineRS,
  title={Bovine respiratory syncytial virus ISCOMs-Immunity, protection and safety in young conventional calves.},
  author={Sara H{\"a}gglund and Kefei Hu and Karin Vargmar and Lesly Por{\'e} and Ann-Sophie Olofson and Krister Blod{\"o}rn and Jenna K. Anderson and Parvin Ahooghalandari and John Pringle and Geraldine Taylor and Jean-François Valarcher},
  journal={Vaccine},
  year={2011},
  volume={29 47},
  pages={
          8719-30
        }
}
Bovine respiratory syncytial virus (BRSV) is a major cause of bronchiolitis and pneumonia in cattle and causes yearly outbreaks with high morbidity in Europe. Commercial vaccines against this virus needs improvement of efficacy, especially in calves with BRSV-specific maternally derived antibodies (MDA). We previously reported that an experimental BRSV-ISCOM vaccine, but not a commercial vaccine, induced strong clinical and virological protection in calves with MDA, immunized at 7-15 weeks of… CONTINUE READING
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