Bovine polymorphonuclear cells passively acquire membrane lipids and integral membrane proteins from apoptotic and necrotic cells.

@article{Whale2006BovinePC,
  title={Bovine polymorphonuclear cells passively acquire membrane lipids and integral membrane proteins from apoptotic and necrotic cells.},
  author={Tyler A Whale and Terry K Beskorwayne and Lorne A. Babiuk and Philip Griebel},
  journal={Journal of leukocyte biology},
  year={2006},
  volume={79 6},
  pages={1226-33}
}
Immune cells can acquire membrane fragments and integral membrane proteins from dead and dying cells or in the case of immature dendritic cells, from live cells. While investigating the possibility that bovine polymorphonuclear cells (PMNs) might present antigen, coculture assays confirmed that integral membrane proteins were transferred rapidly and efficiently to bovine PMNs from a variety of apoptotic and necrotic cells. Specifically, we observed that PMNs rapidly acquired proteins such as… CONTINUE READING

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