Bovine immature oocytes acquire developmental competence during meiotic arrest in vitro.

@article{Hashimoto2002BovineIO,
  title={Bovine immature oocytes acquire developmental competence during meiotic arrest in vitro.},
  author={Shu Hashimoto and Naojiro Minami and Ryo Takakura and Hiroshi Imai},
  journal={Biology of reproduction},
  year={2002},
  volume={66 6},
  pages={1696-701}
}
To test the hypothesis that oocytes require time to acquire developmental competence during meiotic arrest, we investigated the effects of butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinase, on the developmental competence of bovine oocytes after in vitro fertilization (IVF) following release from meiotic arrest. In the present study, 4 culture conditions were used: addition of BSA or fetal bovine serum (FBS) under 2 oxygen tensions (5% vs. 20%) during meiotic… CONTINUE READING

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