Bovine ileal intraepithelial lymphocytes represent target cells for Shiga toxin 1 from Escherichia coli.

@article{Menge2004BovineII,
  title={Bovine ileal intraepithelial lymphocytes represent target cells for Shiga toxin 1 from Escherichia coli.},
  author={Christian Menge and Maike Blessenohl and Tobias Eisenberg and Ivonne Stamm and Georg Baljer},
  journal={Infection and immunity},
  year={2004},
  volume={72 4},
  pages={1896-905}
}
The discovery that bovine peripheral lymphocytes are sensitive to Stx1 identified a possible mechanism for the persistence of infections with Shiga toxin (Stx)-producing Escherichia coli (STEC) in the bovine reservoir host. If intraepithelial lymphocytes (IEL) are also sensitive to Stx1, the idea that Stx1 affects inflammation in the bovine intestine is highly attractive. To prove this hypothesis, ileal IEL (iIEL) were prepared from adult cattle, characterized by flow cytometry, and subjected… CONTINUE READING

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Lymphoid follicle

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