Bovine herpes virus type 1 induces apoptosis through Fas-dependent and mitochondria-controlled manner in Madin-Darby bovine kidney cells

@inproceedings{Xu2012BovineHV,
  title={Bovine herpes virus type 1 induces apoptosis through Fas-dependent and mitochondria-controlled manner in Madin-Darby bovine kidney cells},
  author={Xingang Xu and Kuan Zhang and Yong Huang and Li Ding and Guangda Chen and Honglei Zhang and Dewen Tong},
  booktitle={Virology Journal},
  year={2012}
}
Bovine herpesvirus type 1 (BHV-1) is an important pathogen in cattle that is responsible for substantial economic losses. Previous studies suggest that BHV-1 may induce apoptosis in Madin-Darby bovine kidney (MDBK) cells via a mechanism only involving caspases and p53. However, the mechanism for BHV-1-induced MDBK cell apoptosis still requires more research. MDBK was used as a model to study the precise signaling pathways of apoptosis induced by BHV-1 infection. BHV-1 infection activated a Fas… CONTINUE READING
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