Bovine Serum Albumin Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery via Dry Powder Inhalation

@article{Kunda2014BovineSA,
  title={Bovine Serum Albumin Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery via Dry Powder Inhalation},
  author={Nitesh K Kunda and Iman M. Alfagih and Sarah Rachel Dennison and Hesham M Tawfeek and Satyanarayana Somavarapu and Gillian Ann Hutcheon and Imran Y. Saleem},
  journal={Pharmaceutical Research},
  year={2014},
  volume={32},
  pages={1341-1353}
}
Dry powder vaccine delivery via the pulmonary route has gained significant attention as an alternate route to parenteral delivery. In this study, we investigated bovine serum albumin (BSA) adsorbed poly(glycerol adipate-co-ω-pentadecalactone), PGA-co-PDL polymeric nanoparticles (NPs) within L-leucine (L-leu) microcarriers for dry powder inhalation. NPs were prepared by oil-in-water single emulsion-solvent evaporation and particle size optimised using Taguchi’s design of experiment. BSA was… CONTINUE READING
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