Bovine CD2-/NKp46+ cells are fully functional natural killer cells with a high activation status

@article{Boysen2005BovineCC,
  title={Bovine CD2-/NKp46+ cells are fully functional natural killer cells with a high activation status},
  author={Preben Boysen and Ingrid Olsen and Ingvild Berg and Siri Kulberg and Grethe Marie Johansen and Anne Kristine Storset},
  journal={BMC Immunology},
  year={2005},
  volume={7},
  pages={10 - 10}
}
Natural killer (NK) cells in the cow have been elusive due to the lack of specific NK cell markers, and various criteria including a CD3-/CD2+ phenotype have been used to identify such cells. The recent characterization of the NK-specific NKp46 receptor has allowed a more precise definition of bovine NK cells. NK cells are known as a heterogeneous cell group, and we here report the first functional study of bovine NK cell subsets, based on the expression of CD2. Bovine CD2- NK cells, a minor… CONTINUE READING

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Yabuhara A: Later development of Fas ligand-mediated cytotoxicity as compared with granulemediated cytotoxicity during the maturation of natural killer cells

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