Boveri's long experiment: sea urchin merogones and the establishment of the role of nuclear chromosomes in development.

@article{Laubichler2008BoverisLE,
  title={Boveri's long experiment: sea urchin merogones and the establishment of the role of nuclear chromosomes in development.},
  author={Manfred D. Laubichler and Eric H. Davidson},
  journal={Developmental biology},
  year={2008},
  volume={314 1},
  pages={1-11}
}
Theodor Boveri's major intellectual contribution was his focus on the causality of nuclear chromosomal determinants for embryological development. His initial experimental attempt to demonstrate that the character of the developing embryo is determined by nuclear rather than cytoplasmic factors was launched in 1889. The experimental design was to fertilize enucleate sea urchin eggs with sperm of another species that produces a distinguishably different embryonic morphology. Boveri's "hybrid… CONTINUE READING