Boundary precision in the ventral neural tube

  • Katherine Exelby, Edgar Herrera, +1 author James Briscoe
  • Published 2017 in Mechanisms of Development
  • DOI:10.1016/j.mod.2017.04.173
remains a central topic in biology. In particular, the role of signaling dynamics in governing patterning in space and time is still largely unknown. Timing of mesoderm patterning in vertebrate embryos is controlled by amolecular clock, which in mice is composed of signaling oscillations of the Notch, Wnt and FGF pathways While gainand lossof-function… (More)