Boundary and Medial Shape Analysis of the Hippocampus in Schizophrenia

  title={Boundary and Medial Shape Analysis of the Hippocampus in Schizophrenia},
  author={Martin Styner and Jeffrey A. Lieberman and Guido Gerig},
  journal={Medical image analysis},
  volume={8 3},
Statistical shape analysis has become of increasing interest to the neuroimaging community due to its potential to precisely locate morphological changes and thus potentially discriminate between healthy and pathological structures. This paper describes a combined boundary and medial shape analysis based on two different shape descriptions applied to a study of the hippocampus shape abnormalities in schizophrenia. The first shape description is the sampled boundary implied by the spherical… CONTINUE READING