Boulevard of broken dreams: drug approval for older adults with acute myeloid leukemia.

@article{Sekeres2012BoulevardOB,
  title={Boulevard of broken dreams: drug approval for older adults with acute myeloid leukemia.},
  author={Mikkael A. Sekeres and David P Steensma},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2012},
  volume={30 33},
  pages={
          4061-3
        }
}
weeks) plus supportive care or supportive care alone; almost all patients randomly assigned to the control arm (88%) received LDAC. The primary end point was overall survival. With 485 patients enrolled, the hazard ratio for death for decitabine therapy compared with that for control therapy at the time of the preplanned end point was nonsignificant (0.85; 95% CI, 0.69 to 1.04; P .11), although the complete remission rate in the decitabine arm was more than double that in the control arm (16% v… CONTINUE READING
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