Botulism in Metronidazole-Treated Conventional Adult Mice Challenged Orogastrically with Spores of Clostridium botulinum Type

@inproceedings{SugiyamaBotulismIM,
  title={Botulism in Metronidazole-Treated Conventional Adult Mice Challenged Orogastrically with Spores of Clostridium botulinum Type},
  author={Hiroshi Sugiyama}
}
Conventional adult mice were pretreated with metronidazole to make their intestinal tracts receptive to colonization by Clostridium botulinum. These mice, in groups of 10, were fed 0 (controls), 102, 103, 104, or 105 C. botulinum type B spores and were placed for observation in filter-lid cages whose screen floors minimized the amounts offeces available for… CONTINUE READING