Botulinum toxin type A normalizes alterations in urothelial ATP and NO release induced by chronic spinal cord injury.

@article{Smith2008BotulinumTT,
  title={Botulinum toxin type A normalizes alterations in urothelial ATP and NO release induced by chronic spinal cord injury.},
  author={Christopher Patrick Smith and David A Gangitano and Alvaro Munoz and Nilson A. Salas and Timothy B. Boone and Kei Roger Aoki and Joseph Rabinson Francis and George T. Somogyi},
  journal={Neurochemistry international},
  year={2008},
  volume={52 6},
  pages={1068-75}
}
The purpose of this paper was to simultaneously examine changes in urothelial ATP and NO release in normal and spinal cord injured animals as well as in spinal cord injured animals treated with botulinum toxin type A (BoNT-A). Furthermore we correlated changes in transmitter release with functional changes in bladder contraction frequency, and determined the effects of BoNT-A on bladder efferent nerve function. Normal and spinal cord injured rat bladders were injected on day 0 with either… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

New Frontiers of Basic Science Research in Neurogenic Lower Urinary Tract Dysfunction.

The Urologic clinics of North America • 2017
View 9 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 61 references

Effect of stimulation intensity and botulinum toxin isoform on rat bladder strip contractions

C. P. Smith, T. B. Boone, W. C. de Groat, M. B. Chancellor, G. T. Somogyi
Brain Res. Bull • 2003
View 11 Excerpts
Highly Influenced

Differential inhibition by botulinum neurotoxin A of cotransmitters released from autonomic vasodilator neurons.

American journal of physiology. Heart and circulatory physiology • 2001
View 6 Excerpts
Highly Influenced

Evidence for nonvesicular nitric oxide release evoked by nerve activation.

The European journal of neuroscience • 2000
View 4 Excerpts
Highly Influenced

Presynaptic modulation of neurochemical transmission

Progress in Neurobiology • 1979
View 2 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…