Botulinum toxin type A in the treatment of spasticity in cerebral palsy: theoretical and practical foundations of effective therapy.

@article{Sawek2001BotulinumTT,
  title={Botulinum toxin type A in the treatment of spasticity in cerebral palsy: theoretical and practical foundations of effective therapy.},
  author={Jaroslaw Sławek},
  journal={Ortopedia, traumatologia, rehabilitacja},
  year={2001},
  volume={3 4},
  pages={
          541-6
        }
}
Spasticity is one of the constituent elements of upper motor neuron syndrome. For now, it is also the only symptom which is pharmacologically treatable. The pathophysiology of spasticity is very complex, and many aspects remain unclear. The great majority of commonly used oral drugs modulate the activity of receptors and/or neurotransmitters at different levels of the central nervous system. This is perhaps the main reason for the limited effectiveness of these drugs in many cases. Recently a… CONTINUE READING

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