Botulinum toxin injection for hypercontractile or spastic esophageal motility disorders: may high-resolution manometry help to select cases?

@article{Marjoux2015BotulinumTI,
  title={Botulinum toxin injection for hypercontractile or spastic esophageal motility disorders: may high-resolution manometry help to select cases?},
  author={Sophie Marjoux and Charl{\`e}ne Brochard and S Roman and Rodica Gincul and Mael Pagenault and Thierry Ponchon and Alain Ropert and F Mion},
  journal={Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus},
  year={2015},
  volume={28 8},
  pages={735-41}
}
Endoscopic injections of botulinum toxin in the cardia or distal esophagus have been advocated to treat achalasia and spastic esophageal motility disorders. We conducted a retrospective study to evaluate whether manometric diagnosis using the Chicago classification in high-resolution manometry (HRM) would be predictive of the clinical response. Charts of patients with spastic and hypertensive motility disorders diagnosed with HRM and treated with botulinum toxin were retrospectively reviewed at… CONTINUE READING

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