Botulinum toxin in dermatology – beyond wrinkles and sweat

  title={Botulinum toxin in dermatology – beyond wrinkles and sweat},
  author={Uwe Wollina and Helga Konrad and S. Hagen Petersen},
  journal={Journal of Cosmetic Dermatology},
Botulinum toxin (BTX) types A and B have been used with success in cosmetic dermatology and hyperhidrosis treatment. 

[Botulinum toxin A for the treatment of familial benign pemphigus].

Botulinum Neurotoxin Type A in the Treatment of Oily Skin and Acne: Evidence and a Proposed Mechanism

Current evidence suggests that botulinum neurotoxins can be used as a safe and effective treatment modality for acne and other skin disorders related to the overactivity of sebaceous glands.

Therapeutic Hotline: Topical glycopyrrolate: a successful treatment for craniofacial hyperhidrosis and eccrine hidrocystomas

Eccrine hidrocystoma is a benign tumor derived from eccrine sudoriparous glands that has been associated with Graves' disease, Parkinson's disease, and idiopathic craniofacial hyperhidrosis.

The effect of synthetic acetylhexapeptide‐8 (AH8) on sebaceous function

This study aims to evaluate the in vitro and clinical effects of topical acetylhexapeptide‐8 (AH8) on the appearance of oily skin.

Intralesional botulinum toxin-A injection for the treatment of multiple eccrine hidrocystomas

Intralesional botulinum toxin-A for treatment of multiple hidrocystomas is a simple and well-tolerated procedure accompanied by excellent results, a good postoperative course, and no risk of scarring.

Botulinum toxin (Botox) A for reducing the appearance of facial wrinkles: a literature review of clinical use and pharmacological aspect

  • B. Satriyasa
  • Medicine
    Clinical, cosmetic and investigational dermatology
  • 2019
This article provides a literature review regarding the general issue of Botox as a treatment for reducing facial wrinkle, and concludes that Botox is good and safe medicine to reduce the appearance of facial wrinkles.

Over View Regarding Efficacy of Clostridium Botulinum Toxin (Botox) For the Management of Various Pathologies

The results extracted from the review of literature showed that it is safe with minimum side effects to treat many medical and surgical conditions and the insight regarding clinical efficacy and side effects of botulinum toxin was planned.

Botulinum toxin in dermatology – beyond wrinkles and sweat

The toxicology of hydroquinone – relevance to occupational and environmental exposure, and human in vivo and in vitro topical bioavailability, metabolism, and disposition, is studied.

Management of familial benign chronic pemphigus

Treatment options for benign familial chronic pemphigus include topical and/or systemic agents and surgery including laser, which summarizes the available treatment options.



Botulinum toxin A in anal fissures: a modified technique

  • U. WollinaH. Konrad
  • Medicine
    Journal of the European Academy of Dermatology and Venereology : JEADV
  • 2002
Background Anal fissures are common and painful. Botulinum toxin A (BTXA) is considered to be the most potent non‐surgical treatment; however, no attention has been paid to associated hyperhidrosis.

Adjuvant botulinum toxin A in dyshidrotic hand eczema: a controlled prospective pilot study with left–right comparison

  • U. WollinaT. Karamfilov
  • Medicine, Psychology
    Journal of the European Academy of Dermatology and Venereology : JEADV
  • 2002
A prospective pilot study was performed with left–right comparison in order to investigate whether chemical de‐innervation of sudoriferic nerves would be superior to standard therapy with topical corticosteroids.

Psoriasiform eruption from intramuscular botulinum A toxin.

The first case of a psoriasiform eruption temporally related to the injection of botulinum A toxin into the medial rectus muscle to treat an ocular motility disorder is reported, to the authors' knowledge.

Botulinum Toxin Type B (Myobloc)

  • Leslie BaumannLaura Black
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2003
What is currently known about botulinum toxin type B and its efficacy and safety is reviewed.

Atopy in lichen simplex (neurodermatitis cricumscripta)

  • G. Singh
  • Biology
    The British journal of dermatology
  • 1973
SUMMARY A Statistical study of 102 patients with lichen simplex lesions and a large group of controls shows a significant association between this disease and a personal and family history of atopic

Botulinum toxin type A injection in the treatment of lichen simplex: an open pilot study.

It is concluded that lichen simplex-associated pruritus can be overcome by intradermal botulinum toxin A injection.

Minimally Invasive Application of Botulinum Toxin Type A in Nasal Hypersecretion

It is concluded that this minimal invasive method of local botulinum toxin application might be a very effective and safe option for the treatment of nasal hypersecretion of different etiologies.

Evidence-based medicine: botulinum toxin in focal hyperhidrosis

Abstract All studies performed so far indicate that BTX-A is a safe and effective treatment for focal hyperhidrosis of the axillae and palms, for gustatory sweating, and for some other rare

Use of botulinum toxin type A in a case of persistent parotid sialocele.

  • T. ChowS. Kwok
  • Medicine
    Hong Kong medical journal = Xianggang yi xue za zhi
  • 2003
A 52-year-old Chinese man who had a 10-year history of right parotid swelling was reported on, andBotulinum toxin therapy was an effective method of treating persistent sialocele.

Treatment of proctalgia fugax with botulinum A toxin

Botulinum A toxin seems to be a promising treatment for patients with proctalgia fugax, and further trials appear to be worthwhile for this condition, which has been described as incurable.