Botulinum toxin for the treatment of spasticity in multiple sclerosis. New observations.

@article{BorgStein1993BotulinumTF,
  title={Botulinum toxin for the treatment of spasticity in multiple sclerosis. New observations.},
  author={Joanne Borg-Stein and Z M Pine and Jacob R. Miller and Mitchell F. Brin},
  journal={American journal of physical medicine & rehabilitation},
  year={1993},
  volume={72 6},
  pages={364-8}
}
Potential advantages of intramuscular botulinum toxin for the treatment of spasticity include the lack of sensory effects, ability to target specific muscle groups, ability to weaken muscles in a graded fashion and absence of caustic chemicals such as phenol. We describe the use of botulinum toxin for the treatment of severe lower extremity spasticity in two subjects with multiple sclerosis. Both subjects showed an improvement in spasticity, as measured by the modified Ashworth scale, and in… CONTINUE READING