Botulinum toxin for the management of depression: An updated review of the evidence and meta-analysis.

@article{Schulze2021BotulinumTF,
  title={Botulinum toxin for the management of depression: An updated review of the evidence and meta-analysis.},
  author={Jara Schulze and Insa Neumann and Michelle Magid and Eric Finzi and Christopher Sinke and Marc Axel Wollmer and Tillmann H. C. Kr{\"u}ger},
  journal={Journal of psychiatric research},
  year={2021},
  volume={135},
  pages={
          332-340
        }
}
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Has the COVID‐19 pandemic changed attitudes and behaviors concerning cosmetic care and procedures among patients presenting to the dermatology outpatient clinic? A multicenter study with 1437 participants
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References

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Role of Botulinum Toxin in Depression
TLDR
This study suggests that botulinum toxin A can produce significant improvement in depressive symptoms and is a safe adjunctive treatment for patients receiving pharmacotherapy for depression.
Treating depression with botulinum toxin: a pooled analysis of randomized controlled trials.
TLDR
Equalling the status of a meta-analysis, this study increases evidence that a single treatment of BTA into the glabellar region can reduce symptoms of MDD.
Facing depression with botulinum toxin: a randomized controlled trial.
Botulinum Toxin as a Treatment for Depression in a Real-world Setting
TLDR
It is suggested that glabellar BTX injection may also be effective in the treatment of severe depression and in the Treatment of depression in men, when treatment is carried out not just in clinical trials but in real-world settings.
Treatment of major depressive disorder using botulinum toxin A: a 24-week randomized, double-blind, placebo-controlled study.
TLDR
Botulinum toxin A injection in the glabellar region was associated with significant improvement in depressive symptoms and may be a safe and sustainable intervention in the treatment of MDD.
Does Blocking Facial Feedback Via Botulinum Toxin Injections Decrease Depression? A Critical Review and Meta-Analysis
Researchers have proposed that blocking facial feedback via glabellar-region botulinum toxin injections (GBTX) can reduce depression. Random-effects meta-analyses of studies that administered GBTX to
Efficacy and Safety of Botulinum Toxin Type A in the Treatment of Glabellar Lines: A Meta-Analysis of Randomized, Placebo-Controlled, Double-Blind Trials
TLDR
A meta-analysis of prospective, placebo-controlled, double-blind trials of botulinum toxin type A shows that a single 20-unit dose is considered remarkably effective and safe for the treatment of glabellar lines.
Satisfaction of Patients After Treatment With Botulinum Toxin for Dynamic Facial Lines
TLDR
Injections with BTX-A is a satisfying and well-tolerated treatment of dynamic facial lines for all patients in this pilot study.
Efficacy of Botox versus Placebo for Treatment of Patients with Major Depression
TLDR
Botox is effective for treatment of patients with major depression and it has a high safety, and none of the patients experienced side effects.
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