Botulinum toxin for diabetic neuropathic pain: a randomized double-blind crossover trial.

@article{Yuan2009BotulinumTF,
  title={Botulinum toxin for diabetic neuropathic pain: a randomized double-blind crossover trial.},
  author={Rey-Yue Yuan and Jau- Jiuan Sheu and Juming M Yu and Wei Tseng Chen and I J Tseng and Hui Hua Chang and Chaur Jong Hu},
  journal={Neurology},
  year={2009},
  volume={72 17},
  pages={1473-8}
}
BACKGROUND Diabetic neuropathy is a common complication in diabetes, with patients typically experiencing diverse sensory symptoms including dysesthesias in the feet and usually accompanied by sleep disturbance. There is still no comprehensive understanding of the underlying biologic processes responsible for diabetic neuropathic pain. Thus, the current symptomatic therapy remains unsatisfactory. Recent experimental evidence suggests that botulinum toxin type A (BoNT/A) may not only inhibit the… CONTINUE READING

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