Botulinum toxin A in postherpetic neuralgia: a parallel, randomized, double-blind, single-dose, placebo-controlled trial.

@article{Apalla2013BotulinumTA,
  title={Botulinum toxin A in postherpetic neuralgia: a parallel, randomized, double-blind, single-dose, placebo-controlled trial.},
  author={Zoe Apalla and Eleni Sotiriou and A Lallas and Elizabeth Lazaridou and Demetrios Ioannides},
  journal={The Clinical journal of pain},
  year={2013},
  volume={29 10},
  pages={857-64}
}
OBJECTIVES Cumulative evidence support a beneficial effect of botulinum toxin A (BTX-A) in postherpetic neuralgia (PHN). We aimed to assess efficacy, safety, and tolerability of BTX-A in the management of PHN, performing a randomized, double-blind, single-dose, placebo-controlled trial. METHODS Thirty adults with PHN were randomized either to BTX-A or placebo. Severity of pain was evaluated by patients using a visual analogue scale (VAS) and quality of sleep was assessed using a 5-item… CONTINUE READING
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