Botulinum toxin-A improves the rigidity of progressive supranuclear palsy.

@article{Polo1994BotulinumTI,
  title={Botulinum toxin-A improves the rigidity of progressive supranuclear palsy.},
  author={K B Polo and Bahman Jabbari},
  journal={Annals of neurology},
  year={1994},
  volume={35 2},
  pages={237-9}
}
Botulinum toxin-A (botox) can improve spasticity and decrease painful spasms in the affected limbs of patients with multiple sclerosis. We report significant improvement of muscle rigidity in the upper limbs after focal administration of botulinum toxin A to 2 patients with progressive supranuclear palsy.