Botulinum Toxin Type B in Piriformis Syndrome

@article{Lang2004BotulinumTT,
  title={Botulinum Toxin Type B in Piriformis Syndrome},
  author={Amy M Lang},
  journal={American Journal of Physical Medicine \& Rehabilitation},
  year={2004},
  volume={83},
  pages={198-202}
}
  • Amy M Lang
  • Published 1 March 2004
  • Medicine
  • American Journal of Physical Medicine & Rehabilitation
Lang AM: Botulinum toxin type B in piriformis syndrome. Am J Phys Med Rehabil 2004;83:198–202. ObjectiveTo evaluate the clinical safety and efficacy of botulinum toxin type B (MYOBLOC) in reducing myofascial pain associated with piriformis syndrome. DesignThis was a single-center, outpatient, open-label study of patients with piriformis syndrome. Subjects were treated unilaterally or bilaterally, depending on their symptoms. Evaluations and procedures were performed by a single examiner who was… 
Botulinum Toxin Treatment of Piriformis Syndrome
TLDR
Two double-blind, placebo-controlled studies have strongly supported the efficacy of onabotulinumtoxinA in management of piriformis syndrome and limited open studies suggest that type B toxin (rimaB) is also effective.
Botulinum toxin injections for low-back pain and sciatica.
TLDR
There is low quality evidence that BoNT injections improved pain, function, or both better than saline injections and very low qualityevidence that they were better than acupuncture or steroid injections.
Clinical use of non-a botulinum toxins: botulinum toxin type B
TLDR
Botulinum neurotoxin type B (BT, BT-B) has been used as NeuroBloc/MyoBloc since 1999 and is associated with substantial antigenicity problems originating from a particular low specific biological potency.
Evidence for the Use of Botulinum Toxin in the Chronic Pain Setting—A Review of the Literature
TLDR
It does appear that BTX is useful in selected patients, and its duration of action may exceed that of conventional treatments, and this seems a promising treatment that must be further evaluated.
Injection for Piriformis Syndrome
TLDR
Clinicians should be aware that there are many etiological factors involved, which it may be possible to modify or treat, and most patients respond to conservative measures, including nerve blocks.
New indications for botulinum toxin in rheumatology.
Botox Therapy for Ischemic Digits
TLDR
Vascular function is abnormal in patients with Raynaud's phenomenon and Botox yielded a distinct improvement in perfusion and reduction in pain in patients failing conservative management, although its mechanism is unknown.
Piriformis syndrome, diagnosis and treatment
TLDR
The use of botulinum toxin (BTX) to treat piriformis syndrome supports the prevailing pathoanatomic etiology of the condition and suggests a promising future for BTX in the treatment of other myofascial pain syndromes.
Manual of Botulinum Toxin Therapy: Use of botulinum toxin in musculoskeletal pain and arthritis
TLDR
Clinical evidence from large controlled trials is largely lacking, mixed, or negative in regard to the efficacy of botulinum toxins for neck and back pain, but side effects can be seen at the higher doses used for cervicothoracic and lumbosacral pain.
Botulinum Toxin for the Treatment of Myofascial Pain Syndromes Involving the Neck and Back: A Review from a Clinical Perspective
TLDR
A content analysis of the clinical trials and systematic reviews of MPS found that botulinum toxin could be useful in specific myofascial regions such as piriformis syndrome and in patients with refractory MPS that has not responded to other my ofascial injection therapies.
...
...

References

SHOWING 1-10 OF 25 REFERENCES
Botulinum Toxin Type A Use in Piriformis Muscle Syndrome: A Pilot Study
TLDR
VAS data suggest that intramuscular piriformis injection with 100 units of botulinum toxin type A can reduce pain to a greater extent than similar injections with vehicle alone.
Electrophysiologic evidence of piriformis syndrome.
Posttraumatic piriformis syndrome: diagnosis and results of operative treatment.
TLDR
Patients who have blunt trauma to the buttock and then have signs and symptoms that are suggestive of lumbar nerve-root compression may have posttraumatic piriformis syndrome.
Perisciatic Injection of Steroid for the Treatment of Sciatica due to Piriformis Syndrome
TLDR
A perisciatic injection of steroid using simple landmarks and utilizing a nerve stimulator to locate and inject near the sciatic nerve and into the piriformis muscle is described.
[The piriformis syndrome].
A rare mentioned and therefore and often overlooked cause of low back pain with sciatica. The piriformis muscle arises from the anterior surface of the sacrum and inserts on the superior border of
The piriformis muscle syndrome: a simple diagnostic maneuver.
TLDR
The maneuver described in this report was helpful in diagnosing the piriformis syndrome because it relies on contraction of the muscle, rather than stretching, which the author believes better reproduces the actual syndrome.
Unusual cause of 'piriformis muscle syndrome'.
TLDR
A case of a 40-year-old woman presenting with signs and symptoms suggestive of piriformis muscle syndrome following a gynecologic procedure performed in the dorsal lithotomy position is described.
Recognizing specific characteristics of nonspecific low back pain.
A retrospective review of 1293 cases of low back pain treated over a 12-year period revealed that sacroiliac joint syndrome and posterior joint syndromes were the most common referred-pain syndromes,
Magnetic resonance imaging findings in piriformis syndrome: a case report.
TLDR
A 30-year-old woman, affected by a severe scoliosis, who developed a persistent buttock pain resembling that of PS is reported, which was confirmed by magnetic resonance imaging of the pelvis, which showed an enlargement of the left piriformis muscle with an anterior isplacement of the sciatic nerve.
Piriformis syndrome: pathogenesis, diagnosis, and treatment.
TLDR
The mechanism by which piriformis syndrome causes sciatic neuritis is described and neuritis from radiculitis is differentiated, the treatment of which often results in the "failed disk syndrome".
...
...