Botryllus schlosseri allorecognition: tackling the enigma.

  title={Botryllus schlosseri allorecognition: tackling the enigma.},
  author={Daryl A. Taketa and Anthony W. De Tomaso},
  journal={Developmental and comparative immunology},
  volume={48 1},
Allorecognition has been well-studied in the context of vertebrate adaptive immunity and recognition of the Major Histocompatibility Complex (MHC), which is the central event of vertebrate immune responses. Although allorecognition systems have been identified throughout the metazoa, recent results have shown that there is no apparent conservation or orthologous relationship between the mechanisms underlying this phenomenon in different organisms. Thus the origin of the vertebrate adaptive… CONTINUE READING

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