Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy

Abstract

The hematopoietic Granulocyte-Colony Stimulating Factor (G-CSF) plays a crucial role in controlling the number of neutrophil progenitor cells. Its function is mediated via the G-CSF receptor, which was recently found to be expressed also in the central nervous system. In addition, G-CSF provided neuroprotection in models of neuronal cell death. Here we used… (More)
DOI: 10.1186/1471-2202-10-49

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@article{Frank2008BothSA, title={Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy}, author={Tobias Frank and Johannes Cm Schlachetzki and Bettina G{\"{o}ricke and Katrin Meuer and Gundula Rohde and Gunnar P. H. Dietz and Mathias B{\"a}hr and Armin Schneider and Jochen Hans Weishaupt}, journal={BMC Neuroscience}, year={2008}, volume={10}, pages={49 - 49} }