Both prenatal and postnatal factors contribute to the effects of maternal stress on offspring behavior and central 5-hydroxytryptamine receptors in the rat.

@article{Peters1988BothPA,
  title={Both prenatal and postnatal factors contribute to the effects of maternal stress on offspring behavior and central 5-hydroxytryptamine receptors in the rat.},
  author={Daniel A Peters},
  journal={Pharmacology, biochemistry, and behavior},
  year={1988},
  volume={30 3},
  pages={669-73}
}
Litters from stressed and control females were cross-fostered at birth to determine whether the effects of maternal stress on the offspring originated prenatally or during the neonatal period. Offspring of stressed females reared by control mothers from birth showed a reduced behavioral response to injections of the 5-hydroxytryptamine (5-HT) agonist 5-methoxy-N,N-dimethyltryptamine (5-MeODMT), increased 5-HT2 receptor binding in cerebral cortex and increased open field activity when tested at… CONTINUE READING

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