Both of the beta-subunit carbohydrate residues of follicle-stimulating hormone determine the metabolic clearance rate and in vivo potency.

Abstract

FSH is a glycoprotein hormone required for the development and maturation of the ovarian follicle and for spermatogenesis. FSH is glycosylated at asparagine residues 52 and 78 on the alpha-subunit and residues 7 and 24 on the beta-subunit. In vitro, the carbohydrate residue at position alpha 52 is required for signal transduction. To define the contribution… (More)

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Cite this paper

@article{Bishop1995BothOT, title={Both of the beta-subunit carbohydrate residues of follicle-stimulating hormone determine the metabolic clearance rate and in vivo potency.}, author={Lilli A Bishop and T. V. Nguyen and Peter R. Schofield}, journal={Endocrinology}, year={1995}, volume={136 6}, pages={2635-40} }