Both muscle-specific and ubiquitous nuclear factors are required for muscle-specific expression of the myosin heavy-chain beta gene in cultured cells.

@article{Shimizu1992BothMA,
  title={Both muscle-specific and ubiquitous nuclear factors are required for muscle-specific expression of the myosin heavy-chain beta gene in cultured cells.},
  author={Nobuyoshi Shimizu and Evelyn Dizon and Radovan Zak},
  journal={Molecular and cellular biology},
  year={1992},
  volume={12 2},
  pages={619-30}
}
Expression of the myosin heavy-chain beta gene is controlled by multiple cis-acting regulatory elements in the 5' flanking region; two of these, referred to as A (-276 to -263) and B (-207 to -180), are essential for conferring muscle-specific activation on homologous and heterologous promoters. Here we report on the identification of nuclear protein… CONTINUE READING