Both intestinal and hepatic lipoprotein production are stimulated by an acute elevation of plasma free fatty acids in humans.

@article{Duez2008BothIA,
  title={Both intestinal and hepatic lipoprotein production are stimulated by an acute elevation of plasma free fatty acids in humans.},
  author={H{\'e}l{\`e}ne Duez and Beno{\^i}t Lamarche and Ren{\'e} Val{\'e}ro and Mirjana Pavlic and Spencer D. Proctor and Changting Xiao and Linda Szeto and Bruce W. Patterson and Gary F. Lewis},
  journal={Circulation},
  year={2008},
  volume={117 18},
  pages={2369-76}
}
BACKGROUND Hepatic lipoprotein production has been shown previously to be regulated by free fatty acid (FFA) flux to the liver, whereas intestinal lipoprotein production is stimulated mainly by ingested fat absorbed from the intestinal lumen. Emerging evidence indicates that intestinal lipoprotein production is increased in insulin resistance and type 2 diabetes mellitus, conditions that are associated with increased levels of circulating FFAs. Here we investigated whether short-term elevation… CONTINUE READING

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