Both extremes of arterial carbon dioxide pressure and the magnitude of fluctuations in arterial carbon dioxide pressure are associated with severe intraventricular hemorrhage in preterm infants.

@article{Fabres2007BothEO,
  title={Both extremes of arterial carbon dioxide pressure and the magnitude of fluctuations in arterial carbon dioxide pressure are associated with severe intraventricular hemorrhage in preterm infants.},
  author={Jorge G Fabres and Waldemar A. Carlo and Vivien Phillips and George Howard and Namasivayam Ambalavanan},
  journal={Pediatrics},
  year={2007},
  volume={119 2},
  pages={299-305}
}
OBJECTIVE The goal was to test the hypothesis that extremes of PaCO2 during the first 4 days after birth are associated with severe intraventricular hemorrhage (grades 3 and 4). METHODS A single-center retrospective review of clinical and blood gas data in the first 4 postnatal days for 849 infants with birth weights of 401 to 1250 g was performed. The univariate and multivariate relationships of severe intraventricular hemorrhage with maximal and minimal PaCO2, PaCO2 averaged over time (time… CONTINUE READING

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