Both dorsal and ventral spinal cord pathways contribute to overground locomotion in the adult rat.

@article{Loy2002BothDA,
  title={Both dorsal and ventral spinal cord pathways contribute to overground locomotion in the adult rat.},
  author={David N Loy and Jason F. Talbott and Stephen M. Onifer and Michael D. Mills and Darlene A Burke and Jessica B Dennison and Lili C Fajardo and David S. K. Magnuson and Scott R Whittemore},
  journal={Experimental neurology},
  year={2002},
  volume={177 2},
  pages={575-80}
}
Identification of long tracts responsible for spontaneous locomotion is critical for spinal cord injury (SCI) repair strategies. We recently demonstrated that extensive demyelination of adult rat thoracic ventral columns, ventromedial, and ventrolateral white matter produces persistent, significant open-field hindlimb locomotor deficits. Locomotor movements resulting from stimulation of the pontomedullary locomotor region are inhibited by dorsolateral funiculus (DLF) lesions suggesting that… CONTINUE READING

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