BotB (botulinum toxin type B): evaluation of safety and tolerability in botulinum toxin type A-resistant cervical dystonia patients (preliminary study).

@article{Truong1997BotBT,
  title={BotB (botulinum toxin type B): evaluation of safety and tolerability in botulinum toxin type A-resistant cervical dystonia patients (preliminary study).},
  author={Daniel D. Truong and Paul A. Cullis and Cathy O'Brien and Martin Koller and Trinidad Villegas and Joetta DeSwarte Wallace},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={1997},
  volume={12 5},
  pages={772-5}
}
Botulinum toxin (BTX) injection is considered the treatment of choice for patients with cervical dystonia (torticollis). We conducted a pilot, open-label, dose-escalation study with BTX type B in 12 patients who no longer responded clinically to injections with BTX type A. At the doses tested, BTX type B was safe and well tolerated without evidence of dose-limiting toxicity in this patient population. Mild-to-moderate adverse events generally resolved quickly and included asthenia, pain, nausea… CONTINUE READING

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