Boswellic acids target the human immune system-modulating antimicrobial peptide LL-37.

Abstract

The antimicrobial peptide LL-37 is the sole member of the human cathelicidin family with immune system-modulating properties and roles in autoimmune disease development. Small molecules able to interact with LL-37 and to modulate its functions have not been described yet. Boswellic acids (BAs) are pentacyclic triterpene acids that are bioactive principles… (More)
DOI: 10.1016/j.phrs.2015.09.002

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