Boswellic acid attenuates asthma phenotype by downregulation of GATA3 via nhibition of PSTAT6.

  title={Boswellic acid attenuates asthma phenotype by downregulation of GATA3 via nhibition of PSTAT6.},
  author={X. R. Zhou and J G Cai and W W Zhu and H. Y. Zhao and K. Wang and Xing-hua Zhang},
  journal={Genetics and molecular research : GMR},
  volume={14 3},
To study the role of boswellic acid in reducing asthma phenotype severity and the relationship between the expression of pSTAT6 and GATA3, thirty-six mice were randomly divided into normal control group, asthma group, and boswellic acid group (treatment group). The asthma model was established through an intraperitoneal injection of sensitization liquid (0.15 mL aluminum hydroxide gel at 88.67 mg/mL and 0.05 mg ovalbumin). pSTAT6 and GATA3 expression levels in peripheral blood were detected by… Expand

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