Boswellia resin: from religious ceremonies to medical uses; a review of in‐vitro, in‐vivo and clinical trials

@article{Moussaieff2009BoswelliaRF,
  title={Boswellia resin: from religious ceremonies to medical uses; a review of in‐vitro, in‐vivo and clinical trials},
  author={Arieh Moussaieff and Raphael Mechoulam},
  journal={Journal of Pharmacy and Pharmacology},
  year={2009},
  volume={61}
}
Objectives Despite its historical‐religious, cultural and medical importance, Boswellia has not been thoroughly studied, and gaps still exist between our knowledge of the traditional uses of the resin and the scientific data available. Here we review the pharmacology of Boswellia resin and of the small molecules identified as the active ingredients of the resin. 
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References

SHOWING 1-10 OF 130 REFERENCES
Analgesic effect of the gum resin of Boswellia serata Roxb.
Abstract Studies on the pharmacology of the gum resin of Boswellia serrata Roxb. showed that its sedative and analgesic effects reside in the non-phenolic fraction. This fraction produced analgesicExpand
The Yoga of Herbs: An Ayurvedic Guide to Herbal Medicine
TLDR
This book contains explanation and classification of herbs, which includes many of the most commonly used western herbs with a profound ayurvedic perspective. Expand
Boswellic acids in chronic inflammatory diseases.
  • H. Ammon
  • Chemistry, Medicine
  • Planta medica
  • 2006
TLDR
Clinical studies suggest efficacy in some autoimmune diseases including rheumatoid arthritis, Crohn's disease, ulcerative colitis and bronchial asthma using Oleogum resins from BOSWELLIA species. Expand
[Is H15 (resin extract of Boswellia serrata, "incense") a useful supplement to established drug therapy of chronic polyarthritis? Results of a double-blind pilot study].
TLDR
Treatment with H15 showed no measurable efficacy and there was no subjective, clinical or laboratory parameter showing a significant or clinically relevant change from baseline or difference between both groups at any time point of observation. Expand
Frankincense and myrrh as remedies in children.
TLDR
The long history of this unusual treatment with frankincense and myrrh is outlined, demonstrating that for several millenia such agents have been employed in a number of medical contexts, as well as in the perfume and incense industries. Expand
Acetyl-11-keto-β-boswellic acid, a constituent of a herbal medicine from Boswellia serrata resin, attenuates experimental ileitis
TLDR
Oral therapy with the Boswellia extract or AKBA significantly reduces macroscopic and microcirculatory inflammatory features normally associated with indomethacin administration, indicating that the anti-inflammatory actions of the Bos Wellia extract in IBD may be due in part to boswellic acids such as AKBA. Expand
Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study.
TLDR
The data show a definite role of gum resin of Boswellia serrata in the treatment of bronchial asthma and improvement of disease as evident by disappearance of physical symptoms and signs. Expand
Boswellic acids: biological actions and molecular targets.
TLDR
This review summarizes the biological actions of BAs on the cellular and molecular level and attempts to put the data into perspective of the beneficial effects manifested in animal studies and trials with human subjects related to inflammation and cancer. Expand
Metabolism of Boswellic Acids in Vitro and in Vivo
TLDR
This study indicates that the efficacy of B. serrata extract may be enhanced by increasing the bioavailability of AKBA, the main active ingredients of boswellic acids, which is not deacetylated to KBA. Expand
Mechanisms underlying the anti-inflammatory actions of boswellic acid derivatives in experimental colitis.
TLDR
The findings demonstrated an anti-inflammatory effect of sAKBA and indicated that P-selectin-mediated recruitment of inflammatory cells is a major site of action for this novel anti- inflammatory agent. Expand
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