Boronic Acid-Based Approach for Separation and Immobilization of Glycoproteins and Its Application in Sensing

@article{Wang2013BoronicAA,
  title={Boronic Acid-Based Approach for Separation and Immobilization of Glycoproteins and Its Application in Sensing},
  author={Xiaojin Wang and N. Xia and L. Liu},
  journal={International Journal of Molecular Sciences},
  year={2013},
  volume={14},
  pages={20890 - 20912}
}
Glycoproteins influence a broad spectrum of biological processes including cell-cell interaction, host-pathogen interaction, or protection of proteins against proteolytic degradation. The analysis of their glyco-structures and concentration levels are increasingly important in diagnosis and proteomics. Boronic acids can covalently react with cis-diols in the oligosaccharide chains of glycoproteins to form five- or six-membered cyclic esters. Based on this interaction, boronic acid-based ligands… Expand
Boronic acids for sensing and other applications - a mini-review of papers published in 2013
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