Boronated protohaemins: synthesis and in vivo antitumour efficacy.


The conjugates of porphyrin macrocycles with boron-containing polyhedra are under investigation as agents for binary treatment strategies of cancer. Aiming at the design of photoactive compounds with low-to-zero dark toxicity, we synthesized a series of carboranyl and monocarbon-carboranyl derivatives of protohaemin IX using the activation of porphyrin… (More)


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@article{Olshevskaya2006BoronatedPS, title={Boronated protohaemins: synthesis and in vivo antitumour efficacy.}, author={Valentina A. Ol'shevskaya and Roza G. Nikitina and Andrei V Zaitsev and Valentina N Luzgina and Elena G Kononova and Tamila G Morozova and Valentina V Drozhzhina and Oleg G. Ivanov and Mikhail A. Kaplan and Valery N. Kalinin and Alexander Capital A Cyrillic Shtil}, journal={Organic & biomolecular chemistry}, year={2006}, volume={4 20}, pages={3815-21} }