Boron-Doped Diamond Microelectrodes Reveal Reduced Serotonin Uptake Rates in Lymphocytes from Adult Rhesus Monkeys Carrying the Short Allele of the 5-HTTLPR.

@article{Singh2010BoronDopedDM,
  title={Boron-Doped Diamond Microelectrodes Reveal Reduced Serotonin Uptake Rates in Lymphocytes from Adult Rhesus Monkeys Carrying the Short Allele of the 5-HTTLPR.},
  author={Y Sanatomba Singh and Lauren E Sawarynski and Heather M Michael and Robert E. Ferrell and Michael A. Murphey-Corb and Greg M Swain and Bhavik Anil Patel and Anne Milasincic Andrews},
  journal={ACS chemical neuroscience},
  year={2010},
  volume={1 1},
  pages={49-64}
}
Uptake resolved by high-speed chronoamperometry on a second-by-second basis has revealed important differences in brain serotonin transporter function associated with genetic variability. Here, we use chronoamperometry to investigate variations in serotonin transport in primary lymphocytes associated with the rhesus serotonin transporter gene-linked polymorphism (rh5-HTTLPR), a promoter polymorphism whose orthologs occur only in higher order primates including humans. Serotonin clearance by… CONTINUE READING
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