Boric acid as a protector against paclitaxel genotoxicity.

  title={Boric acid as a protector against paclitaxel genotoxicity.},
  author={Hasan Turkez and Abdulgani Tatar and Ahmet Hacimuftuoglu and Ebru Ozdemir},
  journal={Acta biochimica Polonica},
  volume={57 1},
Paclitaxel (PAC) is an anticancer drug used for treatments of breast, ovarian and lung cancers. However, little data is available in the literature on its potential genotoxicity on healthy human cells. On the other hand, boron deficiency and supplementation exert important biological effects in human and animal tissues. The biological effects of dietary boron are defined, but its interaction with PAC is not known for therapeutic uses. The aim of the present study was to determine whether boric… CONTINUE READING
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