Bordetella species are distinguished by patterns of substantial gene loss and host adaptation.

@article{Cummings2004BordetellaSA,
  title={Bordetella species are distinguished by patterns of substantial gene loss and host adaptation.},
  author={Craig A. Cummings and Mary M Brinig and Paul W. Lepp and Simone van de Pas and David A. Relman},
  journal={Journal of bacteriology},
  year={2004},
  volume={186 5},
  pages={1484-92}
}
Pathogens of the bacterial genus Bordetella cause respiratory disease in humans and animals. Although virulence and host specificity vary across the genus, the genetic determinants of this diversity remain unidentified. To identify genes that may underlie key phenotypic differences between these species and clarify their evolutionary relationships, we performed a comparative analysis of genome content in 42 Bordetella strains by hybridization of genomic DNA to a microarray representing the… CONTINUE READING